Clostridioides difficile (formally Clostridium difficile, or C. diff) infection (CDI) is considered a worldwide threat with major consequences for morbidity, mortality and healthcare costs. This educational booklet concentrates on the key information needed to understand, diagnose, control, and treat CDI. Healthcare settings likely contributed to the transmission of C. difficile strains, in particular those with epidemic potential, due to overuse of antibiotics, infection prevention practices, and confusion about when, where and how best to test for evidence of C. difficile infection.
Improved control of C. difficile requires a greater understanding of the pathogen, the at-risk hosts and how transmission occurs, improved use of detection and diagnosis methods, and optimized treatment options.
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